Gene interactions and pathways from curated databases and text-mining

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IRS2 — TCF7

Text-mined interactions from Literome

Yang et al., Mol Biol Cell 2010 : In contrast, PKR regulates IRS2 , another major IRS family protein in the liver, at the transcriptional rather than the posttranslational level, and this effect is mediated by the transcription factor , FoxO1, which has been previously shown to be regulated by insulin and plays a significant role in glucose homeostasis and energy metabolism
Liu et al., PloS one 2012 (Diabetes Mellitus, Type 2) : IRS-2 expression is stimulated by the transcription factor cAMP response element binding protein ( CREB ) and we recently demonstrated that Ca ( 2+ ) /calmodulin dependent kinase 4 (CaMK4) is upstream of CREB activation in ß-cells