Gene interactions and pathways from curated databases and text-mining

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KLF10 — TGFB1

Text-mined interactions from Literome

Cao et al., J Biol Chem 2009 (Atherosclerosis) : KLF10 overexpressing CD4 ( + ) CD25 ( - ) T cells induced both TGF-beta1 and Foxp3 expression, an effect associated with reduced T-Bet ( Th1 marker ) and Gata3 ( Th2 marker ) mRNA expression ... Mechanistic studies demonstrate that in response to TGF-beta1, KLF10 can transactivate both TGF-beta1 and Foxp3 promoters, implicating KLF10 in a positive feedback loop that may promote cell-intrinsic control of T cell activation ... Mechanistic studies demonstrate that in response to TGF-beta1, KLF10 can transactivate both TGF-beta1 and Foxp3 promoters, implicating KLF10 in a positive feedback loop that may promote cell-intrinsic control of T cell activation
Tachibana et al., J Clin Invest 1997 (Pancreatic Neoplasms) : In addition, we show that the expression of TIEG is regulated by TGFbeta1 as an early response gene in pancreatic epithelial cell lines