Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Wen et al., Oncogene 2013 (Breast Neoplasms...) : Moreover, we showed that AA-stimulated cell proliferation and angiogenesis required mTOR activity and that the effect of AA was mediated by lipoxygenase (LOX) but not cyclooxygenase-2 (COX-2)
Guadall et al., Front Biosci (Elite Ed) 2011 : Both mTOR blockade and HIF-1alpha knockdown slightly prevented LOX up-regulation by hypoxia, suggesting that HIF-1alpha is only partially responsible for this effect