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LTB — MAPK1
Text-mined interactions from Literome
Tong et al., Biochem Biophys Res Commun 2005
(Pancreatic Neoplasms) :
LTB4 also
stimulated phosphorylation of p38
MAPK ; however, the p38 MAPK inhibitor, SB203580, failed to block LTB4 stimulated growth
Eckert et al., Vet Immunol Immunopathol 2009
(Inflammation) :
We determined that the endogenous chemoattractant
LTB ( 4 ) transiently
activated p38
MAPK and induced chemotaxis of equine primary neutrophils
Campos et al., Mol Immunol 2009
:
Although both exogenous LTB ( 4 ) and LTD ( 4 ) enhanced p38 and ERK 1/2 activation,
LTB ( 4 )
required only
ERK 1/2 , while LTD ( 4 ) required only p38 activation ... Endogenous
LTB ( 4 )
contributed to Fc gammaR mediated activation of PKC-alpha,
ERK 1/2 and PI3K, while endogenous cysLTs contributes to activation of PKC-delta, p38 and PI3K
O'Flaherty et al., J Biol Chem 1996
:
Pertussis toxin, but not Ca2+ depletion, inhibited
MAPK responses to 5-oxoETE and
LTB4 , indicating that responses to both agents are coupled through G proteins but not dependent upon Ca2+ transients