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MAPK1 — PCNA

Text-mined interactions from Literome

de la Monte et al., Alcohol Clin Exp Res 1999 : This study explores the roles of the Grb2- and Syp binding motifs of IRS-1 in relation to the inhibitory effects of ethanol on insulin stimulated DNA synthesis, proliferating cell nuclear antigen ( PCNA ) and glyceraldehyde 3-phosphate dehydrogenase ( GAPDH ) expression, and activation of mitogen activated protein kinase ( MAPK ), which is known to be essential for cell proliferation
Kuwada et al., Mol Biol Cell 2000 : The reversal of mAb 225 mediated growth inhibition on fibronectin for the integrin alpha5 transfectants correlated with activation of the EGFR, activation of MAPK , and expression of proliferating cell nuclear antigen
Hanada et al., American journal of physiology. Renal physiology 2001 : The p44/p42 mitogen activated protein kinase ( MAPK ) kinase 1-p44/p42 MAPK had no effect on cyclin E promoter activities, and the cGMP-protein kinase G pathway did not change MAPK activity
Maller et al., Novartis Found Symp 2001 (MAP Kinase Signaling System) : Use of U0126, a new potent inhibitor of MAPK kinase ( MEK ), shows that MAPK activation is essential to inhibit the anaphase promoting complex and cyclin B degradation at the MI/MII transition
Ito et al., Clin Sci (Lond) 2004 : In fibroblasts, activation of MAPK induces the expression of type D cyclin , whereas, in MCs, this induction has not been shown
Alisi et al., J Cell Physiol 2004 : Interestingly, the activity of cyclin-cdk2 complexes is strongly repressed in the presence of PKC and p42/44 MAPK inhibitors
Yue et al., Curr Biol 2004 : In contrast, immunodepletion of Raf-1 and B-Raf, two other MEK activating kinases present in Xenopus egg extracts, had little effect on cyclin stimulated p42 MAPK activation
Yamamoto et al., Dev Biol 2005 (MAP Kinase Signaling System) : Our results indicate that under CSF arrest, Mos/MAPK activity suppresses cyclin B degradation, preventing Cdc2 activity from falling below normal meta-II levels, whereas activation of APC/C-Cdc20 mediated cyclin B degradation at elevated levels of Cdc2 activity prevents Cdc2 activity from reaching excessively high levels
Takakura et al., J Reprod Dev 2005 : Inhibition of mitogen activated protein kinase activity induces parthenogenetic activation and increases cyclin B accumulation during porcine oocyte maturation ... These results indicate that the inhibition of MAPK activity in porcine oocytes did not promote cyclin B degradation but rather suppressed it ; also the decrease in MPF activity in MAPK suppressed porcine oocytes correlated with the conversion of active MPF into inactive pre-MPF
Shen et al., Cancer Chemother Pharmacol 2006 : Exposure of HT-29 cells with both SFN and an antioxidant, either NAC or GSH, completely blocked the SFN mediated activation of these MAPK signaling cascades, regulation of cyclin D1and p21(CIP1) gene expression, and G ( 1 ) phase cell cycle arrest
Park et al., Transplant Proc 2005 : Proliferating cell nuclear antigen expression, fibronectin secretion, and the activation of extracellular signal regulated protein kinase ( ERK ) and p38 MAPK were assessed by Western blot analysis, collagen synthesis by [ ( 3 ) H ] -proline incorporation, and cellular ROS by flow cytometry
Vlotides et al., Mol Endocrinol 2006 (Pituitary Neoplasms) : Phosphatidylinositol 3 kinase, protein kinase C, and MAPK , but not c-Jun N-terminal kinase and Janus activating kinase signaling regulated EGF induced Pttg1, as well as proliferating cell nuclear antigen mRNA expression and entry into S-phase
Weigel et al., Nuclear receptor signaling 2007 : Many of the phosphorylation sites contain Ser/Thr-Pro motifs implicating proline directed kinases such as the cyclin dependent kinases and the mitogen activated kinases ( MAPK ) in receptor phosphorylation
Lee et al., J Nutr Biochem 2009 : Finally, in the G/GO or HX/XO stimulated cell proliferation, the activity of proliferating cell nuclear antigen was significantly blocked by treatment with ZPDC glycoprotein as well as protein kinase C inhibitor and mitogen activated protein kinase inhibitors
Albanese et al., J Biol Chem 1995 : Cyclin D1 promoter activity was stimulated by overexpression of mitogen activated protein kinase ( p41MAPK ) or c-Ets-2 through the proximal 22 base pairs
VanRenterghem et al., J Biol Chem 1994 : Previously pp60v-src, cyclin A, p39mos, and maturation promoting factor ( composed of Cdc2 and cyclin B ) have been shown to activate mitogen activated protein kinase ( MAPK ) and MAPK kinase ( MEK ) in cell-free extracts of Xenopus oocytes ... In addition, preincubation of extracts with cAMP dependent protein kinase (PKA) blocks stimulation of MAPK by cyclin , p21V12ras, PKC, or pp60v-src, by at least 50 %, but stimulation by c-Mos is unaffected
Abrieu et al., EMBO J 1997 : Suppressing down-regulation of MAPK at fertilization, for example by constitutively activating the upstream MAPK cascade, specifically suppresses cyclin B-cdc2 kinase activation and its consequence, entry into first mitosis
Nakamura et al., J Neuropathol Exp Neurol 1998 (Amyotrophic Lateral Sclerosis...) : To investigate whether these inclusions are related to proline directed protein kinases that have been associated with neuronal inclusion bodies in some other neurodegenerative diseases, we immunohistochemically probed tissue samples from MSA brains with a panel of antibodies against cyclin dependent kinases and mitogen activated protein kinase