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MMP2 — PTEN
Text-mined interactions from Literome
Zhang et al., J Biol Chem 2004
(Carcinoma, Lewis Lung) :
MMP-2 induction was
blocked by the PI 3-kinase inhibitors LY294002 and wortmannin, by overexpression of a dominant negative Akt or wild-type
PTEN ( phosphatase and tensin homologue deleted on chromosome 10 ), and by rapamycin
Furukawa et al., Int J Oncol 2006
(Brain Neoplasms...) :
Ad5CMV-PTEN transfer into the glioma cell lines lacking the wild-type gene product decreased the levels of matrix metalloproteinase (MMP)-2 mRNA and
inhibited the enzymatic activities of
MMP-2 and MMP-9
Tian et al., Oncol Rep 2010
(Carcinoma, Hepatocellular...) :
On the molecular level, overexpression of
PTEN suppressed expression of
matrix metalloproteinase (MMP)-2 and -9 in HepG2 cells
Chen et al., Nan Fang Yi Ke Da Xue Xue Bao 2013
:
MMP-2/MMP-9 inhibitor III did not obviously
affected the expression of
PTEN , VEGF or Flk-1 as compared with the non transfected or empty vector transfected cells