Gene interactions and pathways from curated databases and text-mining

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IL6 — MRXS5

Text-mined interactions from Literome

Tang et al., Immunology 1999 : Since the nitric oxide ( NO ) and prostaglandins (PGs) induced by LPS might modulate IL-6 release, we examined whether NO and PGs were also involved in the potentiating effect of rat CGRP ( rCGRP ) on LPS induced IL-6 release from mouse macrophages
Walch et al., Endocrinology 2002 : PGs alone have no ( IL-1alpha and IL-1beta ) or a modest ( IL-6 ) effect on IL mRNA levels
Kyburz et al., Arthritis Rheum 2003 (Arthritis, Rheumatoid...) : Anti-TLR-2 monoclonal antibodies significantly inhibited production of IL-6 and IL-8 induced by stimulation with PGs
Bamba et al., Aliment Pharmacol Ther 2003 : Effects of PGs on the production of other cytokines such as interleukin (IL)-6 and IL-8 have been controversial ... Additionally, effects of these PGs on the production of IL-6 and IL-8, and modulation of these actions by Reb were studied
Travassos et al., EMBO Rep 2004 : Finally, we show that elicited peritoneal murine macrophages do not produce tumour necrosis factor-alpha or interleukin-6 in response to purified PGs , suggesting that PG detection is more likely to occur intracellularly ( through Nod1/Nod2 ) rather than from the extracellular compartment
Navarra et al., Neuroendocrinology 1992 : In the present study, we have characterized the production of PGs from the rat hypothalamus in vitro, and investigated the effects of IL-1 beta and IL-6 , as well as the neurotransmitters norepinephrine, acetylcholine and 5-hydroxytryptamine, on the acute release of PGs , using a well validated acute hypothalamic incubation system
Leal-Berumen et al., J Immunol 1995 : In this study we examined the hypothesis that mast cell IL-6 production can be selectively regulated by PGs