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IFNG — MSC

Text-mined interactions from Literome

Luan et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2007 : MSC caused a sharp decrease of cytokine secretion in IL-2 and IFN-gamma
Zheng et al., Rheumatology (Oxford) 2008 (Arthritis, Rheumatoid) : The effects of both MSCs and MSC-chondrocytes on the proliferation, activation-antigen expression ( CD69 and CD25 ) and cytokine production [interferon-gamma ( IFN-gamma ), tumour necrosis factor-alpha (TNF-alpha), interleukin (IL)-10 and IL-4 ] of CII-reactive T cells in RA patients were investigated with the stimulation of CII or otherwise
Sundin et al., J Immunother 2009 (Graft vs Host Disease) : Although MSC up-regulated lymphocyte gene expression of CD25, IFN-gamma , FoxP3, CTLA-4, and IL-10, they failed in both unprimed and primed responders to induce CD25+ ( activated ) or CD57+ ( effector ) CD4+ or CD8+ T-lymphocyte subsets and only inconsistently induced FoxP3+ regulatory T-lymphocytes
Gao et al., Cancer Lett 2010 (Carcinoma, Renal Cell...) : Further studies showed that the anti-tumor activity of the MSC/IL-12 was dependent on the presence of natural killer ( NK ) cells and IFN-gamma in this experimental setting
Maggini et al., PloS one 2010 : Using mouse thioglycolate elicited peritoneal macrophages ( M ) stimulated with LPS, we found that MSC markedly suppressed the production of the inflammatory cytokines TNF-alpha, IL-6, IL-12p70 and interferon-gamma while increased the production of IL-10 and IL-12p40
Schurgers et al., Arthritis Res Ther 2010 (Arthritis, Experimental...) : Whereas MSC inhibit anti-CD3 induced proliferation of T cells in vitro, an effect partially mediated by IFN-gamma , MSC do not influence in vivo T cell proliferation nor the disease course of CIA