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NDN — TP53
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
IRef Biogrid Interaction:
NDN
—
TP53
(physical association, affinity chromatography technology)
Huang et al., J Neurosci 2013*
-
IRef Biogrid Interaction:
NDN
—
TP53
(direct interaction, two hybrid)
Taniura et al., J Biol Chem 1999*
-
IRef Biogrid Interaction:
NDN
—
TP53
(direct interaction, pull down)
Taniura et al., J Biol Chem 1999*
-
IRef Hprd Interaction:
TP53
—
NDN
(in vitro)
Taniura et al., J Biol Chem 1999*
-
IRef Hprd Interaction:
TP53
—
NDN
(two hybrid)
Taniura et al., J Biol Chem 1999*
-
IRef Ophid Interaction:
NDN
—
TP53
(aggregation, interologs mapping)
Brown et al., Bioinformatics 2005
-
IRef Ophid Interaction:
NDN
—
TP53
(aggregation, confirmational text mining)
Taniura et al., J Biol Chem 1999*
Text-mined interactions from Literome
Lafontaine et al., PloS one 2012
(Cell Transformation, Neoplastic...) :
While Necdin is induced following p53 activation with different genotoxic stresses,
Necdin induction by PyLT did not
involve p53 activation or the Rb-binding site of PyLT
Lafontaine et al., BMC cancer 2012
:
This result suggests that
Necdin potentially
attenuate p53 signaling in response to genotoxic stress in human cells and supports similar results describing an inhibitory function of Necdin over p53 dependent growth arrest in mice