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MYLIP — NFKB1

Text-mined interactions from Literome

Taganov et al., Proc Natl Acad Sci U S A 2006 : NF-kappaB dependent induction of microRNA miR-146 , an inhibitor targeted to signaling proteins of innate immune responses
Chen et al., Oncogene 2008 (Ovarian Neoplasms) : Regulation of IKKbeta by miR-199a affects NF-kappaB activity in ovarian cancer cells
Wang et al., Cancer Cell 2008 (Rhabdomyosarcoma) : Results demonstrate that in myoblasts, miR-29 is repressed by NF-kappaB acting through YY1 and the Polycomb group
Bazzoni et al., Proc Natl Acad Sci U S A 2009 (Inflammation) : Among the 3 different genes encoding miR-9 precursors in humans, we show that LPS selectively induces the transcription of miR-9-1 located in the CROC4 locus, in a MyD88- and NF-kappaB dependent manner ... In PMN and monocytes, LPS regulates NFKB1 at both the transcriptional and posttranscriptional levels, and a conserved miR-9 seed sustained a miR-9 dependent inhibition of the NFKB1 transcript ... Overall, these data suggest that TLR4 activated NF-kappaB rapidly increases the expression of miR-9 that operates a feedback control of the NF-kappaB dependent responses by fine tuning the expression of a key member of the NF-kappaB family
Xiao et al., J Infect Dis 2009 (Helicobacter Infections...) : H. pylori was able to increase the miR-155 expression in gastric epithelial cell lines and gastric mucosal tissues, and nuclear factor-kappaB (NF-kappaB) and activator protein-1 (AP-1) pathway were required for the induction of miR-155
Liu et al., Proc Natl Acad Sci U S A 2009 (Inflammation) : Expression of miR-147 was greater after cellular activation by TLR4 than after engagement of either TLR2 or TLR3, suggesting that maximal induction of miR-147 required activation of both NF-kappaB and IRF3
Ohdaira et al., Comput Biol Chem 2009 (Lung Neoplasms) : Using a luciferase reporter assay, we also showed that hsa-miR-601 specifically repressed nuclear factor-kappaB (NF-kappaB) transcription factor dependent reporter expression, a key component of the immune-oncogenesis pathway
Gao et al., Cancer 2010 (Adenocarcinoma...) : Overexpression of miR-218 also inhibited NF-kappaB transcriptional activation and transcription of cyclooxygenase -2, a proliferative gene regulated by NF-kappaB
Marquez et al., Am J Physiol Gastrointest Liver Physiol 2010 : It has been previously reported that NF-kappaB upregulates the miR-21 precursor transcript ... Using NF-kappaB reporter assays, we determined that miR-21 overexpression inhibits NF-kappaB signaling
Jurkin et al., J Immunol 2010 (Bacterial Infections) : Inversely, silencing of miR-146a in LCs enhanced TLR2 dependent NF-kappaB signaling
Mott et al., J Cell Biochem 2010 : Finally, activation of NF-kappaB signaling, via ligation of Toll-like receptors, also repressed mir-29b expression and promoter function
Xu et al., J Biol Chem 2011 : miR-365 , a novel negative regulator of interleukin-6 gene expression, is cooperatively regulated by Sp1 and NF-kappaB
Ghose et al., PloS one 2011 (Huntington Disease) : Regulation of miR-146a by RelA/NFkB and p53 in STHdh ( Q111 ) /Hdh ( Q111 ) cells, a cell model of Huntington 's disease ... We conclude that ( i ) miR-125b and miR-150 target p53, which in turn regulates RelA/NFkB and miR-146a expressions ; ( ii ) reduced miR-125b and miR-150 expressions, increased p53 level and decreased RelA/NFkB and miR-146a expressions originate from mutant HTT ( iii ) p53 directly or indirectly regulates the expression of miR-146a
Li et al., BMC molecular biology 2012 (Esophageal Neoplasms) : Reporter assay further showed that NF-kappaB induced miR-34a transcriptional activity was reduced by p53 impairment
Crone et al., Molecular cancer 2012 (Disease Models, Animal...) : Lysophosphatidic acid (LPA) induces NF-kappaB activation via this pathway and over-expression of miR-146a inhibited LPA induced NF-kappaB activation, reduced LPA induced expression of tumor promoting cytokines and growth factors and inhibited monocyte attraction
Panguluri et al., PloS one 2013 (Diabetes Mellitus...) : This miR-301 mediated regulation of Kv4.2 is independent of NFkB and Irx5 and modulates Kv4.2 by direct binding on Kv4.2 3'untranslated region ( 3'-UTR )