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UCSC Genome Browser Gene Interaction Graph
Gene interactions and pathways from curated databases and text-mining

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MET — NOX4

Text-mined interactions from Literome

Park et al., Biochem J 2001 : In addition, 5,6-dichloro-1-beta-o-ribofuranosyl benzimidazole, a CK2 inhibitor, potentiates formyl-Met-Leu-Phe induced NADPH oxidase activity in DMSO differentiated HL-60 cells
Ammendola et al., Free Radic Biol Med 2004 : We investigated in IMR90 cells the effects of N-formyl-Met-Leu-Phe ( N-fMLP ) and WKYMVm ( W peptide ) on activation of the NADPH oxidase-like enzyme
Tyagi et al., Antioxid Redox Signal 2009 : Met increased NADPH-oxidase-4 (NOX-4) expression and mitigated thioredxion-1(Trx-1) expression
Volk et al., J Innate Immun 2011 (MAP Kinase Signaling System...) : PMN generated reactive oxygen species ( ROS ) in response to TNF-a alone, and NADPH oxidase activity increased in response to stimulation with formyl-Met-Leu-Phe after priming
Thelen et al., J Clin Invest 1988 : It thus appears that f-Met-Leu-Phe can lead to maximum activation of the NADPH-oxidase , and that this response is not influenced by IFN gamma