Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Pelletier et al., Cancer Res 2007 : Nucleophosmin protein accumulation was dependent on mammalian target of rapamycin (mTOR) activation, as rapamycin completely prevented nucleophosmin induction
Marzec et al., Oncogene 2007 (Lymphoma, T-Cell) : The NPM/ALK induced mTOR activation is transduced through the mitogen induced extracellular kinase ( MEK ) /extracellular signal regulated kinase ( ERK ) signaling pathway and, to a much lesser degree, through the phosphatidylinositol 3-kinase (PI3K)/protein kinase B ( Akt ) pathway