Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Krauss et al., Cancer Res 2008 (Neoplasms) : Here, we show that protein phosphatase 2A (PP2A) , its regulatory subunit, alpha4, and rapamycin, an inhibitor of the mammalian target of rapamycin kinase complex 1 ( mTORC1 ), regulate the nuclear localization and transcriptional activity of GLI3
Lee et al., Cell Mol Life Sci 2009 : Galectin-1 induced phospho-Akt and -mTOR was inhibited by PP2 , ERas siRNA, caveolin-1 siRNA and Mbeta-CD
Magnaudeix et al., Neurobiol Aging 2013 : In addition, PP2A blockade resulted in the activation of the negative regulator of autophagy mammalian target of rapamycin complex 1 and 5 ' adenosine monophosphate ( AMP ) -activated protein kinase ( AMPK ) and led to intraneuronal accumulation of p62- and ubiquitin positive protein inclusions, likely due to autophagy downregulation