Dey et al., Exp Cell Res 2005
:
These data suggest a distinct requirement for CSK in the regulation of NGF/TrkA activation of RAS, RAC , ERK, and AKT via the differential control of SFKs in the orchestration of neuronal differentiation
Wang et al., Biochem Soc Trans 2006
(Second Messenger Systems) :
This represents the first example of a Rac-GAP regulated directly by DAG in response to the activation of a tyrosine kinase receptor , and suggests a previously unappreciated role for this lipid as a negative modulator of Rac signalling