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OPN1LW — TCF7
Text-mined interactions from Literome
Adamson et al., J Virol 1999
:
In addition, the
Z-CBP interaction may
control host cellular
transcription factor activity through competition for limiting amounts of cellular CBP
Song et al., Biochem Biophys Res Commun 2002
:
Transcription coactivator
CBP has direct DNA binding activity and
stimulates transcription factor DNA binding through small domains
Waltzer et al., Nature 1998
:
Drosophila
CBP represses the transcription factor
TCF to antagonize Wingless signalling ... Although CBP is a coactivator of other transcription factors, our data show that
CBP represses
TCF
Kallio et al., EMBO J 1998
:
However, nuclear localization per se was not sufficient for transcriptional activation, since fusion of HIF-1alpha to the heterologous GAL4 DNA binding domain generated a protein which showed constitutive nuclear localization but required hypoxic stimuli for function as a
CBP dependent
transcription factor