Gene interactions and pathways from curated databases and text-mining

◀ Back to MTOR


Text-mined interactions from Literome

Weimbs et al., Cell cycle (Georgetown, Tex.) 2006 (Polycystic Kidney Diseases) : In ADPKD, defects in PC1 would lead to constitutive activation of mTOR , and the affected cells would be engaged in a permanent state of futile repair leading to the formation and growth of renal cysts
Aguiari et al., Am J Nephrol 2013 (Polycystic Kidney, Autosomal Dominant) : Furthermore, PC1 loss of function also induces activation of mTOR and EGFR signaling