Gene interactions and pathways from curated databases and text-mining

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FGF2 — PECAM1

Pathways - manually collected, often from reviews:

  • OpenBEL Selventa BEL large corpus: PECAM1 → FGF2 (increases)
    Evidence: FGF2 [50] and FGF8b [17] can enhance endothelial cell reorganization onMatrigel.The process requires the activation of the proteolytic machinery, including type IV collagenase(s) and TIMPs production [51] as well as uPA and PAI-1 upregulation [52], a6b1 integrin receptor engagement [53], PECAM-1 [54], and activation of the small GTPase Rac [55].