Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
PECAM1
→
FGF2
(increases)
Evidence: FGF2 [50] and FGF8b [17] can enhance endothelial cell reorganization onMatrigel.The process requires the activation of the proteolytic machinery, including type IV collagenase(s) and TIMPs production [51] as well as uPA and PAI-1 upregulation [52], a6b1 integrin receptor engagement [53], PECAM-1 [54], and activation of the small GTPase Rac [55].