Xu et al., J Biol Chem 2011
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Amino acid- and glucose induced PLD and mTORC1 activity were also dependent on the GTPases RalA and ARF6 and the type III phosphatidylinositol-3-kinase hVps34 Yoon et al., J Cell Biol 2011
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Furthermore, amino acids stimulate PLD1 translocation to the lysosomal region where mTORC1 activation occurs in an hVps34 dependent manner, and this translocation is necessary for mTORC1 activation