Gene interactions and pathways from curated databases and text-mining

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PLD1 — WNT6

Text-mined interactions from Literome

Kang et al., Cancer Res 2010 (Neoplasms) : PLD1 expression and activity was enhanced by treatment with Wnt3a and glycogen synthase kinase-3 inhibitors, and the Wnt pathway regulated transcription factors beta-catenin and TCF-4 were required for this effect
Kang et al., PloS one 2010 (Colorectal Neoplasms...) : Suppressing PLD using gene silencing or selective inhibitor blocked the ability of beta-catenin to transcriptionally activate PLD and other Wnt target genes by preventing formation of the beta-catenin/TCF-4 complex, whereas tactics to elevate intracellular levels of phosphatidic acid, the product of PLD activity, enhanced these effects