Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

Kim et al., Mol Cell Biol 2008 : The antiapoptotic effect of GIP in beta cells is therefore partially mediated through a novel mode of transcriptional regulation of Bcl-2 involving cAMP/PKA/AMPK dependent regulation of CREB/TORC2 activity
Spirli et al., Hepatology 2010 (Cysts...) : CONCLUSION : These data demonstrate that PKA dependent up-regulation of mTOR has a central role in the proliferative, antiapoptotic, and pro-angiogenic effects of IGF1 and VEGF in polycystin-2-defective mice
Xie et al., Cell Signal 2011 : In this study, we show that the pharmacological elevation of [ cAMP ] ( i ) in mouse embryonic fibroblasts ( MEFs ) and human embryonic kidney 293 (HEK293) cells inhibits mTORC1 activation via a PKA dependent mechanism