Gene interactions and pathways from curated databases and text-mining

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PRKAG1 — PSMD1

Text-mined interactions from Literome

Wang et al., Circ Res 2010 : Analysis of aortic endothelial cells from AMPKalpha2 ( -/- ) mice and human umbilical vein endothelial cells expressing dominant negative AMPK or AMPKalpha2-specific siRNA revealed that loss of AMPK activity increased NAD ( P ) H oxidase subunit expression ( gp91(phox), p47(phox), p67(phox), NOX1 and -4 ), NAD ( P ) H oxidase mediated superoxide production, 26S proteasome activity, IkappaBalpha degradation, and nuclear translocation of NF-kappaB ( p50 and p65 ), whereas AMPK activation by AICAR or overexpression of constitutively active AMPK had the opposite effect
Xu et al., PloS one 2012 : In contrast, AMPK activation increases levels of O-GlcNAcylated PA700/S10B , likely through enhanced association of PA700 with O-GlcNAc transferase (OGT), the enzyme that catalyzes protein O-GlcNAcylation