Gene interactions and pathways from curated databases and text-mining

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NOTCH2 — PTBP2

Text-mined interactions from Literome

Heinz et al., Blood 2006 : Additionally, Notch induced generation of interstitial-type DCs was associated with PU.1 up-regulation
Wang et al., J Biol Chem 2009 (Hypersensitivity, Delayed) : Therefore, Notch signaling is essential for DCs to transit from a dendrite ( low ) MHC II ( low ) immature state into a dendrite ( high ) MHC II ( high ) mature state, during the lipopolysaccharide induced DC maturation, most likely through the up-regulation of CXCR4
Ito et al., PLoS Pathog 2011 (Orthomyxoviridae Infections) : We demonstrate here that macrophages, but not dendritic cells (DCs) , increased Notch ligand Delta-like 1 (Dll1) expression following influenza virus challenge
Gentle et al., J Immunol 2012 : We demonstrate that concurrent Notch and TLR stimulation results in a unique cytokine profile in mouse bone-marrow derived DCs characterized by enhanced IL-10 and IL-2, and reduced IL-12 expression compared with TLR ligation alone