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HSPB1 — PTGS2

Text-mined interactions from Literome

Lasa et al., Mol Cell Biol 2000 (MAP Kinase Signaling System) : The MAPKAPK-2 substrate hsp27 may be involved in stabilization, as beta-globin-Cox-2 transcripts were partially stabilized by phosphomimetic mutant forms of hsp27
Liu et al., Cell Immunol 2010 (Inflammation) : In the present study, both overexpression and RNA interference experiments indicated that HSP27 increased LPS induced expression of iNOS and COX-2 and release of NO/PGE2 through enhancing NF-kappaB but not MAPK activation ... The effects of HSP27 on LPS induced iNOS/COX-2 expression and relative signaling cascade were closely related with the phosphorylation of HSP27