Gene interactions and pathways from curated databases and text-mining

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ICAM1 — RAC1

Text-mined interactions from Literome

Chen et al., J Pharmacol Exp Ther 2003 : In contrast, Ad.N17Rac1 inhibited TNF-alpha induced NF-kappaB-driven HIV ( kappaB ) ( 4 ) -CAT and p288VCAM-Luc promoter activity, suggesting that N17Rac1 inhibits TNF-alpha induced VCAM-1, E-selectin, and ICAM-1 through suppressing NF-kappaB mediated transactivation
Miho et al., Cardiovasc Res 2005 : Dominant negative Ras and Rac1 , but not Rho, inhibited thrombin induced JNK activation and ICAM-1 promoter activity
Harokopakis et al., J Immunol 2006 : Furthermore, fimbriae stimulated monocyte adhesion to HUVEC and transmigration across HUVEC monolayers ; both activities required TLR2 and Rac1 signaling and were dependent upon ICAM-1 and the high-affinity state of CD11b/CD18
Wu et al., Biochem Pharmacol 2013 (Inflammation) : The Rac-1 activation and ROS liberation mediated TNF stimulated NF-?B activation and the subsequent VCAM-1 and ICAM-1 expression