◀ Back to RAF1

RAF1 — RASA1

Pathways - manually collected, often from reviews:

• OpenBEL Selventa BEL large corpus: RASA1 → RAF1 (increases)
  Evidence: Raf significantly increased the protein levels of p120RasGAP within 24–72 hr (Figure 4B).
• WikiPathways EPO Receptor Signaling: Complex of GRB2-RAF1-SOS1-IRS2-JAK2-IRS1-RASA1 → MAP2K1 (activation)

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Hprd Interaction: Complex of 33 proteins (in vivo) Kozutsumi et al., Oncogene 1994*

Text-mined interactions from Literome

Lin et al., Cell Microbiol 2003 (MAP Kinase Signaling System) : Both tyrosine phosphatase activity and GAP activity were responsible for SptP inhibition of Raf ( Y340D ) -induced ERK activation, but only GAP activity was responsible for inhibition of the membrane localized forms of Raf-1
Zhang et al., Nature 1993 : Raf-1 ( 1-257 ) binds GTP-Ras in preference to GDP-Ras, and inhibits Ras-GAP activity