Gene interactions and pathways from curated databases and text-mining

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BMP2 — RGMB

Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Halbrooks et al., Journal of molecular signaling 2007 : Here, we investigate whether RGMa, RGMb , and RGMc play required roles in BMP and TGFbeta signaling in the mouse myoblast C2C12 cell line
Kanomata et al., Genes Cells 2009 : DRAGON , a GPI anchored membrane protein, inhibits BMP signaling in C2C12 myoblasts ... We report here that DRAGON/RGMb , a member of the RGM family, suppressed BMP signaling in C2C12 myoblasts via a novel mechanism ... DRAGON even suppressed BMP signaling induced by constitutively activated Smad1
Ma et al., J Neurosci 2011 : We used a murine RGMb knock-out to gain insight into the physiological role of RGMb in the DRG, and address whether RGMb mediated modulation of BMP signaling influences sensory axon regeneration ... We show that diminished BMP signaling in vivo, achieved either through RGMb deletion or BMP inhibition with Noggin, retarded early axonal regeneration after sciatic nerve crush injury