Gene interactions and pathways from curated databases and text-mining

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CDC73 — SBF1

Text-mined interactions from Literome

Wijnen et al., Mol Cell Biol 2002 : The Cln3-Cdc28 complex somehow activates SBF and MBF, but there was no evidence for direct phosphorylation of SBF/MBF by Cln3-Cdc28 or for a stable complex between SBF/MBF and Cln3-Cdc28 ... Cln3-Cdc28 may activate SBF and MBF indirectly, perhaps by phosphorylating some intermediary protein
Koch et al., Genes Dev 1996 : Activation of transcription at the G1/S boundary requires Cdc28 and one of the G1 cyclins Cln1-Cln3, whereas repression of SBF regulated genes in G2 requires the association of Cdc28 with G2-specific cyclins Clb1-Clb4. Using in vivo genomic footprinting, we show that SBF ( Swi4/Swi6 ) binding to SCB elements ( Swi4/Swi6 cell cycle box ) in the CLN2 promoter is cell cycle regulated