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IFNG — SCG2

Text-mined interactions from Literome

Matsuse et al., Ann Allergy Asthma Immunol 1999 (Asthma...) : We compared the effects of SCG on interleukin (IL)-5 and interferon (IFN)-gamma production by sensitized PBMCs with that of dexamethasone ( Dex )
Harada et al., J Interferon Cytokine Res 2002 : In this study, we examined interferon-gamma (IFN-gamma) induction by SCG from splenocytes in DBA/2 mice in vitro ... In the splenocytes derived from almost all inbred strains of mice except for DBA/1 and DBA/2 mice, IFN-gamma production was not induced by SCG ... The breeder and genders of DBA/2 mice showed no influence on IFN-gamma induction by SCG ... IFN-gamma was induced by SCG in adherent splenocytes, but IFN-gamma production was most significantly increased by SCG in instances involving coexistence of adherent and nonadherent splenocytes ... It was suggested that soluble factors and cell-cell contact mediate synergistic effects on SCG induced IFN-gamma production
Harada et al., J Interferon Cytokine Res 2004 : The addition of recombinant murine GM-CSF ( rMuGM-CSF ) to spleen cell cultures from various strains of mice synergistically enhanced IFN-gamma , TNF-alpha and IL-12p70 in the presence of SCG
Harada et al., J Interferon Cytokine Res 2006 : We recently found that the splenocytes from naive DBA/1 and DBA/2 mice are potently induced by SCG to produce interferon- gamma (IFN-gamma) , tumor necrosis factor-alpha (TNF-alpha), granulocyte-macrophage colony stimulating factor ( GM-CSF ), and interleukin-12p70 (IL-12p70), and that GM-CSF plays a key biologic role among these cytokines ... Neutralization of IL-12 significantly inhibited the induction of IFN-gamma by SCG
Harada et al., Microbiol Immunol 2006 (Leukopenia) : The levels of interferon-(IFN-)gamma , tumor necrosis factor-(TNF-)alpha, granulocyte-macrophage-colony stimulating factor ( GM-CSF ), interleukin-(IL-) 6 and IL-12p70 were significantly increased by SCG in CY-treated mice ... Neutralizing GM-CSF significantly inhibited the induction of IFN-gamma , TNF-alpha and IL-12p70 by SCG