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PRKAR1A — SCT

Text-mined interactions from Literome

Lesage et al., Hepatology 2002 : Insulin induced activation of PKC alpha, which decreased secretin stimulated cAMP and PKA activity
Francis et al., Am J Physiol Cell Physiol 2007 (Bile Duct Diseases) : In BDL rats, UK 14,304 inhibited secretin stimulated 1 ) bile and bicarbonate secretion, 2 ) expansion of IBDU luminal spaces, and 3 ) cAMP levels, PKA activity, Cl ( - ) efflux, and Cl ( - ) /HCO ( 3 ) ( - ) exchanger activity in cholangiocytes
Glaser et al., Hepatology 2010 (Cholestasis, Extrahepatic...) : In vitro, secretin increased proliferation, PKA activity, and ERK1/2 phosphorylation of large cholangiocytes that was blocked by PKA and mitogen activated protein kinase kinase inhibitors
Mahata et al., Cell Tissue Res 2011 : In agreement, secretin increased PKA activity and induced phosphorylation of CREB and binding to Th CRE, suggesting secretin signaling to transcription via a PKA-CREB pathway
Úriz et al., PloS one 2011 (Choledochal Cyst...) : Experiments with inhibitors and Ca ( 2+ ) -chelator confirmed that the synergistic effect of secretin plus TUDCA involves microtubules, intracellular Ca ( 2+ ), PKCa, PI3K, PKA and MEK pathways ... UDCA is conjugated in order to promote secretin stimulated hydrocholeresis in rats through Ae2, microtubules, intracellular Ca ( 2+ ), PKCa, PI3K, PKA , and MEK
Williams et al., J Neurosci 2012 : Since secretin receptors activate PKA ( Wessels-Reiker et al., 1993 ), we tested the hypothesis that secretin regulates Kv1.2 trafficking in the cerebellum