Teodorczyk-Injeyan et al., J Trauma 1988
(Burns) :
IL2 secretion in response to the T-cell mitogen Staphylococcal protein A (SPA) is significantly decreased in patients with major burns ( n = 10, greater than 20 % total body surface area ) up to 50 days postburn in comparison with normal control ( greater than 2 to 10 U/ml and 16 to 36 U/ml, respectively )
Shore et al., Clin Exp Immunol 1986
(Acute Disease...) :
Twenty-one patients with rheumatoid arthritis ( RA ) and 12 age and sex matched healthy controls were examined for the ability of their monocytes ( adherent cells, AC ) to spontaneously secrete interleukin 1 (IL-1) and for their peripheral blood mononuclear cells ( PBMC ) to secrete interleukin 2 (IL-2) induced by Staphylococcal Protein A (SPA) Keystone et al., J Rheumatol 1986
(Spondylitis, Ankylosing) :
We examined the spontaneous secretion of interleukin 1 (IL-1) from peripheral blood monocytes and staphylococcal protein A (SPA) induced secretion of interleukin 2 (IL-2) from peripheral blood mononuclear cells from 13 patients with active ankylosing spondylitis and 10 healthy controls
Fleischer et al., J Immunol Methods 1981
:
Staphylococcal Protein A (SpA) induces T cell growth factor (TCGF) production in cultures of human peripheral blood mononuclear cells ( PBMC ) with titers equivalent to those induced by PHA ... TCGF induction by SpA was blocked by addition of human AB-serum or human IgG, as was the mitogenic effect of SpA