Gene interactions and pathways from curated databases and text-mining

◀ Back to BCL3

BCL3 — SKP1

Text-mined interactions from Literome

Jin et al., Mol Reprod Dev 2005 : While SCF up-regulated the expression of the anti-apoptotic proteins Bcl-2 and Bcl-xL , it did the opposite to the pro-apoptotic factor Bax
Hu et al., Am J Physiol Gastrointest Liver Physiol 2008 (Drug-Induced Liver Injury) : SCF inhibited APAP induced hepatocyte apoptosis and increased Bcl-2 and Bcl-xL expression, suggesting that this decrease in hepatocyte apoptosis is mediated through Bcl-2 and Bcl-xL
Rådinger et al., J Immunol 2011 : The decrease in stem cell factor (SCF) mediated survival in the GSK3ß knockdown HuMCs was reflected by enhancement of SCF withdrawal induced apoptosis, as determined by Annexin V staining and caspase cleavage, and this was associated with a pronounced reduction in SCF mediated phosphorylation of Src homology 2 domain containing phosphatase 2 and ERK1/2 and reduced expression of the antiapoptotic proteins Bcl-xl and Bcl-2