Gene interactions and pathways from curated databases and text-mining

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SMN1 — STAT3

Text-mined interactions from Literome

Pechkovsky et al., Am J Pathol 2012 (Idiopathic Pulmonary Fibrosis) : Suppression of STAT3 signaling diminished resistance of IPF LFs to staurosporine induced apoptosis and responsiveness to transforming growth factor ß ( 1 ) but increased basal a-SMA and restored ß ( 3 ) integrin expression in LFs via an ALK-5 dependent, SMAD3/7 independent mechanism
Wu et al., Cell Biochem Funct 2013 : If we inhibit STAT3 activity by STAT3 targeted small molecules, TSLP induced a-SMA and collagen I upregulation can not be detected