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EGFR — SNX6
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Cavet et al., FASEB J 2008
:
In contrast, expression of GIT1 ( CC2 deleted ) and
SNX6 did not
reduce EGFR levels, demonstrating that the interaction between GIT1 and SNX6 was required to regulate EGFR trafficking
Bachleitner-Hofmann et al., Clin Cancer Res 2011
:
In all cell lines,
SNX-2112 led to degradation of MET, HER-2,
EGFR , and AKT, as well as abrogation of Ras/Raf/MEK/MAPK and PI3K/AKT signaling, followed by complete cell cycle arrest