Gene interactions and pathways from curated databases and text-mining

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EGFR — SNX6

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Cavet et al., FASEB J 2008 : In contrast, expression of GIT1 ( CC2 deleted ) and SNX6 did not reduce EGFR levels, demonstrating that the interaction between GIT1 and SNX6 was required to regulate EGFR trafficking
Bachleitner-Hofmann et al., Clin Cancer Res 2011 : In all cell lines, SNX-2112 led to degradation of MET, HER-2, EGFR , and AKT, as well as abrogation of Ras/Raf/MEK/MAPK and PI3K/AKT signaling, followed by complete cell cycle arrest