Gene interactions and pathways from curated databases and text-mining

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Text-mined interactions from Literome

GrinyĆ³ et al., Am J Transplant 2006 : MMF, a reversible inhibitor of inosin monophosphate dehydrogenase ( IMPDH ) acts as an antiproliferative drug ; and SRL , an mTOR ( mammalian target of rapamycin ) inhibitor , inhibits cell proliferation driven by growth factors
Reis et al., Transplant Proc 2009 (Hypertension) : Thus, the hypertensive effects of CsA, a calcineurin inhibitor, and of SRL , an mTOR inhibitor , are associated with impairment of distinct cardiovascular pathways
Kasap , Pediatr Transplant 2011 (Hyperlipidemias...) : SRL , an mTOR inhibitor that inhibits cell cycle progression, represents an important alternative to CNIs, which are still the cornerstones of pediatric solid organ tx
Masri et al., Transplant Proc 2007 : SRL inhibits mammalian target of rapamycin (TOR) , which is an enzyme critical to the immune function