Gene interactions and pathways from curated databases and text-mining

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CASP16 — STC1

Text-mined interactions from Literome

Basini et al., Ann N Y Acad Sci 2009 : Moreover, STC 's effect on cell viability and the modulation of caspase-3 and -7 activities in swine aortic endothelial cells were also examined ... Endothelial cell viability was significantly ( P < 0.001 ) increased, whereas caspase activities were reduced ( P < 0.01 ) by STC
Yun et al., Clin Cancer Res 2012 (Colorectal Neoplasms...) : We found that STC induces apoptosis in these cells in a dose dependent manner and leads to the activation of Fas and caspase-8, cleavage of Bid, mitochondrial damage, and activation of caspase-3