Gene interactions and pathways from curated databases and text-mining

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PIK3CD — TLR4

Text-mined interactions from Literome

Dil et al., Mol Immunol 2009 : Role of phosphoinositide 3-kinase p110 delta in TLR4- and TLR9 mediated B cell cytokine production and differentiation ... TLR4- and TLR9-ligands act in synergy to drive IL-6 and IL-10 production, but not IL-12, and this additive effect is independent of p110 delta signaling
Durand et al., J Immunol 2009 : In these innate-like B cells, p110delta activity mediates BCR-, TLR- and chemoattractant induced activation of the Akt prosurvival kinase, chemoattractant induced migration, and TLR induced proliferation