Gene interactions and pathways from curated databases and text-mining

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CTNNB1 — TNF

Text-mined interactions from Literome

Fuchs et al., Oncogene 1999 : Mutant HOS which lacks the F-box blocked TNF alpha induced degradation of IkappaB as well as GSK3beta mediated degradation of beta-catenin
Swinney et al., J Biol Chem 2002 : A small molecule inhibitor of NF-kappaB dependent cytokine expression was discovered that blocked tumor necrosis factor (TNF) alpha induced IkappaB(alpha) degradation in MM6 cells but not the degradation of beta-catenin in Jurkat cells
Carayol et al., Eur Respir J 2002 : In human bronchial epithelial cells the authors have shown that tumour necrosis factor (TNF)-alpha induced a significant decrease of E-cadherin and beta-catenin expression
Choi et al., Nucleic Acids Res 2007 : We identified a binding site for beta-catenin in the downstream of CRP gene by 3C and confirmed TNF-alpha induced association of beta-catenin and p50 by chromatin immunoprecipitation and co-immunoprecipitation assays
Gertzberg et al., Am J Physiol Lung Cell Mol Physiol 2007 : However, the expression of the EYFP-Y198F beta-actin and EYFP-Y218F beta-actin prevented the effect of TNF on beta-catenin and barrier function
Cernuda-Morollón et al., Methods Mol Biol 2010 (Inflammation) : The method is based on a transmigration assay of human T lymphoblasts through TNF-alpha stimulated human primary endothelial monolayers, a triple fluorescence labelling of F-actin, the adhesion receptor ICAM-1 and the junctional protein beta-catenin and a subsequent acquisition of z-stacks of high-resolution confocal sections