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IGF1 — TNFRSF11B
Text-mined interactions from Literome
Rubin et al., J Clin Endocrinol Metab 2002
:
IGF-I regulates
osteoprotegerin (OPG) and receptor activator of nuclear factor-kappaB ligand in vitro and OPG in vivo ... The half maximal inhibitory dose of IGF-I was reached at 50 micro g/liter ( approximately 6.5 nM ) with no
effect of
IGF-I on
OPG message stability ... In summary, we conclude that
IGF-I in a dose- and time dependent manner
regulates OPG and RANKL in vitro and in vivo
Katopodis et al., Anticancer Res 2009
(Bone Neoplasms...) :
The enhancement of the
OPG expression in PC-3 cells by MG-63 cells is not
mediated by
IGF-1 , IL-6 and TGFbeta1