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IRF6 — TNFSF11

Text-mined interactions from Literome

Kikuchi et al., J Immunol 2001 : Here we investigated the effects of LPS on the gene expression of ODF in mouse osteoblasts and an osteoblast cell line and found that LPS increased the ODF mRNA level
Zou et al., J Bone Miner Res 2002 : However, TNF-a expression was increased also in conditions in which LPS inhibited RANKL osteoclastogenic activity ... LPS inhibits RANKL activity by reducing the expression of RANK and M-CSF receptor and stimulates osteoclastogenesis in RANKL pretreated cells via TNF-alpha
Kikuchi et al., J Dent Res 2003 : These findings indicate that Cot/Tpl2 is essential for LPS induced ERK activation and RANKL induction in osteoblasts
Suda et al., J Immunol 2004 : LPS induced both stimulation of RANKL mRNA expression and inhibition of OPG mRNA expression in osteoblasts ... NS398 blocked LPS induced down-regulation of OPG mRNA expression, but not LPS induced up-regulation of RANKL mRNA expression, suggesting that down-regulation of OPG expression by PGE ( 2 ) is involved in LPS induced osteoclast formation in the cocultures
Wada et al., Bone 2004 : These suggest that LPS stimulates both OPG and RANKL expression in HPLF by up-regulating IL-1 beta and TNF-alpha
Tiranathanagul et al., J Periodontol 2004 (Alveolar Bone Loss) : The upregulation of RANKL but not OPG by the LPS was found in both transcription and translation and could be reduced by indomethacin
Coon et al., J Endod 2007 (Bone Resorption...) : LPS and endodontic materials caused a decrease in both RANKL and OPG expression in WT cells
Kaneko et al., Prostaglandins Leukot Essent Fatty Acids 2007 : We conclude that RANKL stimulated osteoclastogenesis can be enhanced by PGE2 and LPS though direct effects on the hematopoietic cell lineage and that these effects may be mediated in part by induction of COX-2 and enhanced intracellular PG production
Kirkwood et al., Curr Drug Metab 2009 (Disease Progression...) : LPS , an outer membrane constituent of periodontal pathogenic bacteria, stimulates the production of inflammatory cytokines IL-1beta, TNFalpha, IL-6 and RANKL either directly or indirectly
Chakravarti et al., Blood 2009 (Bone Resorption) : We show that lipopolysaccharide (LPS) , a toll-like receptor 4 ligand, up-regulated the expression of membrane RANKL in human blood neutrophils and murine air pouch derived neutrophils
Krajewski et al., APMIS 2009 : In conclusion the data demonstrate that stimulation of PDL cells with P. gingivalis LPS leads to an increased release of sRANKL, rather than increased RANKL expression
Jang et al., Phytother Res 2010 (Bone Resorption) : NS-398 inhibited the effect of LPS on RANKL and OPG expression in osteoblasts
Miyasato et al., Hiroshima J Med Sci 2013 (Bone Resorption...) : Further, Dex significantly suppressed the stimulatory effects of LPS on RANKL and Ki-67 expression and on IL-6 and IL-8 production