Pathways - manually collected, often from reviews:
OpenBEL Selventa BEL large corpus:
Complex of BCAR1-PTK2-TNS3
→
EGF
(decreases, BCAR1/PTK2/TNS3 Activity)
Cui et al., Mol Cancer Res 2004* Evidence: Furthermore, tensin3 forms a complex with focal adhesion kinase and p130Cas in MDA-MB-468 cells. Addition of EGF to the cells induces dephosphorylation of these two molecules, leads to disassociation of the tensin3-focal adhesion kinase-p130Cas complex, and enhances the interaction between tensin3 and EGF receptor.
OpenBEL Selventa BEL large corpus:
Complex of EGFR-TNS3
→
EGF
(increases)
Cui et al., Mol Cancer Res 2004* Evidence: Addition of EGF to the cells induces dephosphorylation of these two molecules, leads to disassociation of the tensin3-focal adhesion kinase-p130Cas complex, and enhances the interaction between tensin3 and EGF receptor.
OpenBEL Selventa BEL large corpus:
TNS3
→
EGF
(increases, EGF Activity, TNS3 Activity)
Cui et al., Mol Cancer Res 2004* Evidence: Furthermore, tensin3 forms a complex with focal adhesion kinase and p130Cas in MDA-MB-468 cells. Addition of EGF to the cells induces dephosphorylation of these two molecules, leads to disassociation of the tensin3-focal adhesion kinase-p130Cas complex, and enhances the interaction between tensin3 and EGF receptor.