Gene interactions and pathways from curated databases and text-mining

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TLR4 — VCAM1

Text-mined interactions from Literome

Sawa et al., J Histochem Cytochem 2008 : The LPS induced IL-6, IL-8, VCAM-1 , and ICAM-1 production in LEC was suppressed by the introduction of TLR4-specific small interfering RNA, and also by anti-TLR4 , nobiletin, and CAPE pretreatment
Sawa et al., Cell Tissue Res 2008 : The expression of LTA induced E-selectin, ICAM-1, and VCAM-1 in LEC is suppressed by anti-TLR2 but not by anti-TLR4 and is also suppressed by TLR2-specific short interfering RNA ( siRNA ) but not by siRNA for TLR4
Lee et al., Cell communication and signaling : CCS 2012 : In bacteria induced glomerulonephritis, Toll-like receptor 4 (TLR4) activation by lipopolysaccharide ( LPS, a key component of the outer membranes of Gram negative bacteria ) can increase oxidative stress and the expression of vascular cell adhesion molecule-1 ( VCAM-1 ), which recruits leukocytes to the glomerular mesangium