Gene interactions and pathways from curated databases and text-mining

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AKT3 — VIM

Text-mined interactions from Literome

Strizzi et al., J Cell Sci 2005 (Mammary Neoplasms, Animal) : Treating EpH4/Cripto-1 or HC-11/Cripto-1 mammary cells with exogenous soluble Netrin-1 resulted in increased expression of E-cadherin and UNC5H1, decreased expression of vimentin and decreased activation of Akt as determined by western blotting
Zhu et al., Oncogene 2011 (Neoplasm Invasiveness...) : The binding of AKT ( tail region ) to Vim ( head region ) results in Vim Ser39 phosphorylation enhancing the ability of Vim to induce motility and invasion while protecting Vim from caspase induced proteolysis
Lian et al., J Biol Chem 2012 : Furthermore, inhibition of PI3K/Akt/mTOR signaling, but not canonical Smad signaling, downstream of TGFß, blocked TGFß induced synthesis of vimentin , and inhibited ATF4 dependent Ocn transcription in osteoblasts