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PTK2 — VWF
Pathways - manually collected, often from reviews:
-
Reactome Reaction:
PTK2
→
VWF
(reaction)
Schaller et al., Biochim Biophys Acta 2001, Giuliano et al., Biochem J 2003, Parsons et al., J Cell Sci 2003, Defilippi et al., Trends Cell Biol 2006, Mitra et al., Curr Opin Cell Biol 2006
-
Reactome Reaction:
PTK2
→
VWF
(indirect_complex)
Schaller et al., Biochim Biophys Acta 2001, Mitra et al., Curr Opin Cell Biol 2006
Text-mined interactions from Literome
Mekrache et al., Blood 2003
(von Willebrand Diseases) :
Activation of
pp125FAK by type 2B recombinant
von Willebrand factor binding to platelet GPIb at a high shear rate occurs independently of alpha IIb beta 3 engagement
Yang et al., Mol Cancer Ther 2006
(Liver Neoplasms, Experimental...) :
Compared with HAL alone,
PTK787 combined with HAL significantly prolonged the animal survival, reduced the tumor size, induced more tumor tissue necrosis and apoptosis, and
down-regulated the expression of
von Willebrand factor