Schölzke et al., Eur J Neurosci 2003
:
However, inhibition of the glutamate activated Ca2+ dependent protease calpain by calpeptin completely blocked IkappaBalpha degradation and reduced the nuclear translocation of p65 Liu et al., Apoptosis 2006
(Carcinoma...) :
Since purified m- or mu-calpain degraded NF-kappaB p65 in vitro, it is possible that calpastatin suppressed calpain mediated degradation of NF-kappaB p65