Gene interactions and pathways from curated databases and text-mining

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Pathways - manually collected, often from reviews:

Text-mined interactions from Literome

Cunningham et al., Nature 2007 : Moreover, mTOR and raptor interacted with YY1, and inhibition of mTOR resulted in a failure of YY1 to interact with and be coactivated by PGC-1alpha
Bl├Ąttler et al., Mol Cell Biol 2012 : Mechanistically, mTOR dependent phosphorylation of YY1 resulted in a strong interaction between YY1 and the transcriptional coactivator peroxisome proliferator activated receptor gamma coactivator 1a ( PGC1a ), a major regulator of mitochondrial function