This gene encodes a member of the cytosolic phospholipase A2 group IV family. Members of this family are involved in regulation of membrane tubule-mediated transport. The enzyme encoded by this member of the family plays a role in trafficking through the clathrin-independent endocytic pathway. The enzyme regulates the recycling process via formation of tubules that transport internalized clathrin-independent cargo proteins back to the cell surface. [provided by RefSeq, Jan 2017]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. There is no transcript support for the 5' exon structure in human; this exon combination is inferred based on homologous transcript alignments from mouse GeneID:329502. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1968189, SAMEA1968540 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END##
This track shows known protein-coding and non-protein-coding genes
for organisms other than human, taken from the NCBI RNA reference
sequences collection (RefSeq). The data underlying this track are
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The RNAs were aligned against the human genome using blat; those
with an alignment of less than 15% were discarded. When a single RNA aligned
in multiple places, the alignment having the highest base identity was
identified. Only alignments having a base identity level within 0.5% of
the best and at least 25% base identity with the genomic sequence were kept.
This track was produced at UCSC from RNA sequence data
generated by scientists worldwide and curated by the
NCBI RefSeq project.
BLAT--the BLAST-like alignment tool.
Genome Res. 2002 Apr;12(4):656-64.
PMID: 11932250; PMC: PMC187518
Pruitt KD, Brown GR, Hiatt SM, Thibaud-Nissen F, Astashyn A, Ermolaeva O, Farrell CM, Hart J,
Landrum MJ, McGarvey KM et al.
RefSeq: an update on mammalian reference sequences.
Nucleic Acids Res. 2014 Jan;42(Database issue):D756-63.
PMID: 24259432; PMC: PMC3965018
Pruitt KD, Tatusova T, Maglott DR.
NCBI Reference Sequence (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins.
Nucleic Acids Res. 2005 Jan 1;33(Database issue):D501-4.
PMID: 15608248; PMC: PMC539979