Gene interactions and pathways from curated databases and text-mining

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ADAM11 — IRF6

Text-mined interactions from Literome

Kuroda et al., J Immunol 2001 : MDC production by B cells was equally stimulated by LPS and anti-CD40 Ab, while that by macrophages and dendritic cells was more markedly stimulated by anti-CD40 Ab, and PGE ( 2 ) further enhanced MDC production by these stimulated cells
Yamada et al., J Urol 2005 (Urinary Bladder Neoplasms) : LPS did not induce RT4 cells to produce IP-10 and MDC
Wang et al., Vet Immunol Immunopathol 2007 : Compared with the iDC, the LPS stimulated mDC exhibited a significantly increased expression of IL-1 beta, IL-10, IL-12p40, IL-13, and TNF-alpha
Hung et al., Pediatr Allergy Immunol 2007 : Ketotifen ( 5-50 microM ) significantly down-regulated lipopolysaccharide (LPS) induced MDC , MIG and IP-10 ( p < 0.05, each comparison ) in THP-1 cells and human primary monocytes in a dose dependent manner ... SB203580 [ p38-mitogen activated protein kinase ( MAPK ) inhibitor ] suppressed LPS induced MDC and IP-10 expression, and PD98059 ( ERK-MAPK inhibitor ) could only suppress LPS induced IP-10, but not MDC expression ... These data demonstrate that ketotifen is effective in down regulating LPS induced MDC , MIG and IP-10, which play important roles in the pathogenesis of airway inflammation
Hung et al., Eur Respir J 2008 : Higher doses of salmeterol were required to enhance LPS induced MDC expression in THP-1 cells ... Formoterol- and LPS induced MDC expression was inhibited by budesonide
Baumgart et al., Clin Exp Immunol 2009 (Acute Disease...) : Cytokine secretion of freshly isolated, cultured and lipopolysaccharide (LPS) stimulated highly purified mDC ( purity > 95 % ) was assessed using cytometric bead arrays ( CBA )
Yeh et al., Inflammation 2010 : Nonylphenol and 4-octylphenol were able to suppress LPS induced MDC and IP-10 expression ... Nonylphenol and 4-octylphenol suppressed LPS induced MDC expression in monocytes via, at least in part, the MKK1/2-ERK MAPK pathway and histone H4 acetylation, but not the estrogen receptor
Huang et al., J Food Sci 2010 (Hypersensitivity...) : Our data demonstrated that kaempferol significantly inhibited the lipopolysaccharide (LPS) induced production of monocyte derived chemokine (MDC) , interferon gamma induced protein 10 (IP-10), and interleukin-8 (IL-8) in THP-1 cells